Pro-slavery advocate Nathan Lord argues that the curse of Cain was perpetuated through intermarriage with Ham's line.
Nathan Lord, A Letter of Inquiry to Ministers of the Gospels of All Denominations, on Slavery (Boston, MA: Fetridge and Company, 1860), 7–8
III. Whether slavery is not also a positive institution of Revealed Religion? Whether, in view of the known character of mankind and manifold irregularities of human society, we should not, antecedently, expect to find instances and examples of such an institution, in any recorded history of the Divine government over the disordered world? Whether, accordingly, the cures of Ham did not fall on him and his posterity both on account of his personal obliquities, and as the representative of a race naturally deriving form him, through his forbidden intermarriage with the previously wicked and accursed race of Cain, peculiar propensities, dangerous to themselves and to the other better races, and requiring their subjection and servitude to these other races, in reference to the wise and good ends which God had in view in repeopling the deluged earth?